ASA Abstracts

2012 Annual Meeting Abstracts

October 13-17, 2012
Walter E. Washington Convention Center
Washington D.C.

Special Session - Best of Abstracts: Basic Science

Session #
Date/Time/Location
Title/Authors

SPE08
October 15, 2012
8:00 AM - 10:00 AM
144C
Naloxone Blocks Lipid Rescue of Bupivacaine-induced Cardiotoxicity in a Dose Dependent Manner

Parisa Partownavid, M.D., Soban Umar, M.D.,Ph.D., Siamak Rahman, M.D., Mansoureh Eghbali, Ph.D.

SPE08
October 15, 2012
8:00 AM - 10:00 AM
144C
Unlike Opioids, Ischemic Preconditioning and Isoflurane, Intralipid is Able to Protect Caveolin-3 Knockout Mice Against I/R Injury

Siamak Rahman, M.D., Heidi Fridolfsson, Ph.D., David M. Roth, M.D.,Ph.D., Hemal H. Patel, Ph.D., Mansoureh Eghbali, Ph.D.

Oral Presentations

Session #
Date/Time/Location
Title/Authors

OR 03-1
October 13, 2012
8:00 AM - 9:30 AM
103A
Efficacy of BOTOX Injections for Bilateral Posterior Neck and Cervical Muscle Pain

Jeffrey Loh, M.D., Andrea Nicol, M.D., F. Michael Ferrante, M.D.

OR 09-1
October 13, 2012
10:00 AM - 11:30 AM
103B
Rapid Activation of G-protein Coupled Estrogen Receptor 1 Protects the Heart Against Ischemia/Reperfusion Injury by Inhibiting the mPTP Opening Via PKC/ERK/GSK-3β Pathway

Jean Chrisostome Bopassa, Ph.D., Rong Lu, M.D.,Ph.D., Harpreet Singh, Ph.D., Bjorn Olde, Ph.D., Andree Krust, Ph.D., L.M. Fredrik Leeb-Lundberg, Ph.D., Ligia Toro, Ph.D., Enrico Stefani, M.D.,Ph.D.
OR 09-1
October 13, 2012
10:00 AM - 11:30 AM
103B
Greater Myocardial Susceptibility to Ischemia/Reperfusion Injury in Late Pregnancy may in Part Be Due to Deactivation of Akt/ERK and STAT3 Signaling Pathways

Jingyuan Li, Ph.D., Andrea Iorga, Ph.D., Ji-Youn Youn, Ph.D., Hua Cai, Ph.D., Vera Regitz-Zagrosek, Ph.D., Mansoureh Eghbali, Ph.D.
OR 14-1
October 13, 2012
3:00 PM - 4:30 PM
101
Critical Incidents in the Perioperative Setting: A Survey of US Anesthesiologists' Experience

Colin E. Bauer, M.D., Marjorie Stiegler, M.D., Anahat Dhillon, M.D.
OR 09-2
October 16, 2012
8:00 AM - 9:30 AM
103B
In Vivo and In Vitro Reversal of Pulmonary Vascular Remodeling Associated With Severe Hypertension by Intralipid

Soban Umar, M.D.,Ph.D., Rangarajan D. Nadadur, B.Sc., Salil Sharma, Ph.D., Michelle Afkhami, M.D., Mansoureh Eghbali, Ph.D.

OR 09-2
October 16, 2012
8:00 PM - 9:30 PM
103B
Estrogen Plays a Protective Role in Advanced Heart Failure by Regulating Multiple MicroRNAs Associated With Fibrosis

Salil Sharma, Ph.D., Andrea Iorga, B.S., Rangarajan D. Nadadur, B.S., Mansoureh Eghbali, Ph.D.

Poster Sessions

Session #
Date/Time/Location
Title/Authors

PD 09-1
October 14, 2012
10:00 AM - 11:30 AM
103B
Induced Cardioprotection Against Ischemia Reperfusion Injury is Lost After Kcnma1 Gene Ablation

Ligia Toro, Ph.D., Harpreet Singh, Ph.D., Enrico Stefani, M.D.,Ph.D., Jean C. Bopassa, Ph.D.

PD 06-3
October 17, 2012
10:00 AM - 11:30 AM
101
Predicting Need for Intraoperative Hemodialysis During Liver Transplantation in Patients With Renal Failure

Anahat Dhillon, M.D., Vatche Agopian, M.D., Abbas Rana, M.D., Huy Vo, B.S., Borin Hou, B.S., Ronald Busuttil, M.D.

PO 011-1
October 13, 2012
8:00 AM - 11:00 AM
Hall C-Area A
Anesthesiologists Role, Trust in Anesthesiologists, Knowledge and Fears About Anesthesia Among Patients From an Inner-City County Pre-operative Anesthesia Clinic

Gundappa Neelakanta, M.D., Dustin Nagrampa, Student, Shahrzad Hejazi-Bazargan, Ph.D., Mona Mojtahedzadeh, M.D., Margaret Miller, M.D., Adrienne Law, B.S.

PO 04-1
October 13, 2012
8:00 AM - 11:00 AM
Hall C-Area D
Heparin-coated Pulmonary Artery Catheters Prolong Clotting Time as Measured by Thromboelastometry Without Heparinase Modification

Eujin Kim, M.D., Jason Chua, M.D., Michelle Y. Braunfeld, M.D..

PO 06-2
October 13, 2012
8:00 AM - 11:00 AM
Hall C-Area E
Three Dimensional (Speckle Tracking Based) Strain Imaging Identifies Alterations in Dynamic Left Ventricular Function After Cardiac Surgery

Kimberly Howard-Quijano, M.D., Jonathan Ho, M.D., Ali Salem, M.D., Einat Mazor, Jennifer Scovotti, M.A., Aman Mahajan, M.D.,Ph.D.

PO 09-2
October 13, 2012
1:00 PM - 4:00 PM
Hall C-E-Poster area
Rescue of Pre-existing Severe Pulmonary Hypertension and Cardiovascular Dysfunction by an Apolipoprotein-A1 Mimetic Peptide 4F

Soban Umar, M.D.,Ph.D., Rangarajan D. Nadadur, B.Sc., Kaveh Navab, M.D., Mohamad Navab, Ph.D., Mansoureh Eghbali, Ph.D.

PO 09-2
October 13, 2012
1:00 PM - 4:00 PM
Hall C-E-Poster area
Sudden Cardiac Death and Spontaneous Ventricular Fibrillation Associated With Pulmonary Hypertension-induced Right Heart Failure are Prevented by 17-Beta Estradiol

Soban Umar, M.D.,Ph.D., Aneesh Bapat, M.D., Raymond Chui, B.Sc., Hrayr S. Karagueuzian, Ph.D., Mansoureh Eghbali, Ph.D.

PO 09-2
October 13, 2012
1:00 PM - 4:00 PM
Hall C-E-Poster area
Estrogen Reverses Pulmonary Vascular Remodelling, Elevated Plasma Oxidized Lipids and Eicosanoids Associated With Severe Pulmonary Hypertension

Soban Umar, M.D.,Ph.D., Kaveh Navab, M.D., Samuel H. Wald, M.D., Mohamad Navab, Ph.D., Mansoureh Eghbali, Ph.D.

PO 09-2
October 13, 2012
1:00 PM - 4:00 PM
Hall C-E-Poster area
Protective Role of Endogenous and Exogenous Estrogen in the Development of Experimental Pulmonary Hypertension and Right Ventricular Remodeling

Soban Umar, M.D.,Ph.D., Rangarajan D. Nadadur, B.Sc., Samuel H. Wald, M.D., Gabriel Wong, B.Sc., Mansoureh Eghbali, Ph.D.

PO 09-2
October 13, 2012
1:00 PM - 4:00 PM
Hall C-E-Poster area
Short-Term Estrogen Treatment of Advanced Heart Failure Reverses Cardiac Fibrosis and Inflammation

Andrea Iorga, B.Sc., Rangarajan Nadadur, B.S., Salil Sharma, Ph.D., Jingyuan Li, M.D.,Ph.D., Mansoureh Eghbali, Ph.D.

PO 09-2
October 13, 2012
1:00 PM - 4:00 PM
Hall C-E-Poster area
Estrogen Receptor β Mediates the Anti-Extracellular Matrix Remodeling Effects of Estrogen in the Right Ventricle

Rangarajan Nadadur, B.S., Soban Umar, M.D.,Ph.D., Andrea Iorga, B.S., Mansoureh Eghbali, Ph.D.

PO 09-2
October 13, 2012
1:00 PM - 4:00 PM
Hall C-E-Poster area
Genistein Fails to Rescue Severe Pulmonary Hypertension in the Presence of Estrogen Receptor β Antagonist

Rangarajan Nadadur, B.S., Soban Umar, M.D.,Ph.D., Humann Matori, B.S., Mansoureh Eghbali, Ph.D.

PO 10-1
October 13, 2012
1:00 PM - 4:00 PM
Hall C-Area I
Calcium and Heme Set the BK Channel Intracellular Gating Ring Apparatus Into Different Conformational States.

Taleh Yusifov, Ph.D., Anoosh Javaherian, B.S., Stefan Heinemann, Ph.D., Toshinori Hoshi, Ph.D., Riccardo Olcese, Ph.D.

PO 10-1
October 13, 2012
1:00 PM - 4:00 PM
Hall C-Area K
Relative Transmembrane Segment Rearrangements During Human BK Channel Activation Resolved by Structurally-Assigned Fluorophore/Quencher Pairing

Antonios Pantazis, Ph.D., Riccardo Olcese, Ph.D.

PO 10-1
October 13, 2012
1:00 PM - 4:00 PM
Hall C-Area K
Calcium and Heme Set the BK Channel Intracellular Gating Ring Apparatus Into Different Conformational States.

Taleh Yusifov, Ph.D., Anoosh Javaherian, B.S., Stefan Heinemann, Ph.D., Toshinori Hoshi, Ph.D., Riccardo Olcese, Ph.D.

PO 10-1
October 13, 2012
1:00 PM - 4:00 PM
Hall C-Area K
Pore Blockade Reveals the Voltage Sensor / Pore Interplay in Human BK Channels

Antonios Pantazis, Ph.D., Lu Xu, B.S., Daniel Sigg, M.D.,Ph.D., Riccardo Olcese, Ph.D.

PO 10-1
October 13, 2012
1:00 PM - 4:00 PM
Hall C-Area K
The Human BK Channel Gating Ring is a PIP2 Sensor

Taleh Yusifov, Ph.D., Anoosh Javaherian, B.S., Stefan Heinemann, Ph.D., Toshinori Hoshi, Ph.D., Riccardo Olcese, Ph.D.

PO 10-2
October 14, 2012
1:00 PM - 4:00 PM
Hall C-E-Poster area
BKCa Localization in Brain Mitochondria and Identification of its Molecular Proteome

Harpreet Singh, Ph.D., Enrico Stefani, M.D.,Ph.D., Ligia Toro, Ph.D.

PO 03-1
October 15, 2012
8:00 AM - 11:00 AM
Hall C-Area A
Efficacy of Oblique Versus Anterior-Posterior Lumbar Radiofrequency Ablation Technique for Treatment of Lumbar Facet Arthropathy

Andrea L. Nicol, M.D., John Shin, M.D., Christine Lee, M.D., F. Michael Ferrante, M.D.

PO 04-3
October 16, 2012
8:00 AM - 11:00 AM
Hall C-Area B
Anesthetic considerations for thoracoscopic sympathetic ganglionectomy to treat ventricular tachycardia storm: study of the experience in a single center

Emily Methangkool, M.D., Jason Chua, M.D., Anupama Gopinath, M.D., Aman Mahajan, M.D.,Ph.D.

PO 09-3
October 15, 2012
8:00 AM - 11:00 AM
Hall C-Area C
Probing the Relevance of ICa,L Kinetics on Early Afterdepolarization Susceptibility in Cardiac Myocytes

Roshni V. Madhvani, M.S., Yuanfang Xie, Ph.D., Antonios Pantazis, Ph.D., Alan Garfinkel, Ph.D., Zhillin Qu, Ph.D., James N. Weiss, M.D., Riccardo Olcese, Ph.D.

PO 09-3
October 15, 2012
8:00 AM - 11:00 AM
Hall C-Area C
Angiotensin II Type 1 Receptor Regulates BK Channels Independent of G-protein Activation in Rat Renal Arterial Smooth Muscle Cells

Zhu Zhang, Ph.D., Enrico Stefani, M.D.,Ph.D., Ligia Toro, Ph.D.

PO 09-3
October 15, 2012
8:00 AM - 11:00 AM
Hall C-Area C
Pregnancy-induced Heart Hypertrophy is Associated With Cardiac Structural and Hemodynamic Changes That are Reversed Postpartum

Soban Umar, M.D.,Ph.D., Rangarajan D. Nadadur, B.Sc., Mansour Eghbali, M.D., Marjan Amjedi, M.D., Mansoureh Eghbali, Ph.D.

PO 17-1
October 15, 2012
1:00 PM - 4:00 PM
Hall C-Area K
Respiratory Control and Induction Doses of General Anesthetics in Alcoholic Patients

Zhuang T. Fang, M.D., Wendy Ren, M.D., Dena Yessin, B.S., Victoria Vo, M.D., Jake Ing, M.D., Max Shao, M.D.

PO 14-2
October 16, 2012
8:00 AM - 11:00 AM
Hall C-Area C
Excellence in Communication and Professionalism: Patient and Physician’s Perspectives About the Pre-anesthetic Interaction

Theodora Wingert, M.D., Lucine Torosian, B.S., Andrew Leitner, M.D., Tony Nguyen, M.D., Ali Salehi, M.D., Yue Ming Huang, Ed.D.

PD 04-4
October 16, 2012
1:00 AM - 4:00 AM
Hall C-E-Poster area
Massive Transfusion in Both Pre- and Post-Reperfusion Periods During Orthotopic Liver Transplantation: Incidence, Risk Factors And Outcome

Worapot Apinyachon, M.D., Randolph H. Steadman, M.D., Victor W. Xia, M.D.

PO 09-1
October 17, 2012
1:00 PM - 4:00 PM
Hall C-Area G
Activation of Complex I of the Electron Transfer Chain Favors Mitochondrial Permeability Transition Pore Opening

Enrico Stefani, M.D.,Ph.D., Jean C. Bopassa, Ph.D., Netanel F. Zilberstein, B.Sc., Ligia Toro, Ph.D.

PO 09-1
October 16, 2012
1:00 PM - 4:00 PM
Hall C-Area G
Gonadectomized Mice With XY Sex Chromosome are More Protected Against Ischemia/Reperfusion Injury Compared to XX Mice

Jingyuan Li, Ph.D., Rebecca Watkins, Ph.D., Xuqi Chen, Ph.D., Arthur P. Arnold, Ph.D., Mansoureh Eghbali, Ph.D.

PO 09-1
October 16, 2012
1:00 PM - 4:00 PM
Hall C-Area G
Myocardial Ischemia/Reperfusion Injury in Late Pregnancy Results in Reduced Mitochondrial Function and Increased Superoxide Production

Jingyuan Li, Ph.D., Andrea Iorga, Ph.D., Ji-Youn Youn, Ph.D., Hua Cai, Ph.D., Vera Regitz-Zagrosek, Ph.D., Mansoureh Eghbali, Ph.D.

PO 14-5
October 16, 2012
1:00 PM - 4:00 PM
Hall C-Area I
Is Transesophageal Echocardiography Safe for Patients Undergoing Liver Transplantation?

Christine C. Myo Bui, M.D., Worapot Apinyachon, M.D., Nhat M. To, M.D., Randolph H. Steadman, M.D., Victor W. Xia, M.D.

PO 11-2
October 16, 2012
1:00 PM - 4:00 PM
Hall C-Area K
Do Anesthesia Residents Seek Information to Address Self-Identified Weaknesses After Simulated Crisis Scenarios?

Michelle Y. Arnold, M.D., Sarah Zacharia, MBS, Sebastian Uijtdehaage, Ph.D., Yue Ming Huang, Ed.D., Sara Kim, Ph.D., Jamie Stiner, Majorie Stiegler, M.D.

PO 11-2
October 16, 2012
1:00 PM - 4:00 PM
Hall C-Area K
Anesthesiology Trainees Underrate Performance in High Fidelity Simulation

Marjorie Stiegler, M.D., Anahat Dhillon, M.D., Yue Ming Huang, Ed.D., Sebastian Uijtdehaage, Ph.D., Sarah Zacharia, M.S., Jamie Stiner, Sara Kim, Ph.D.

PO 11-2
October 16, 2012
1:00 PM - 4:00 PM
Hall C-Area K
Resident-led Debriefing Protocol Is Not Sufficient to Prevent Faculty Bias

Marjorie Stiegler, M.D., Sara Kim, Ph.D., Yue Ming Huang, Ed.D., Sebastian Uijtdehaage, Ph.D., Jamie Stiner, Sarah Zacharia, M.S., Anahat Dhillon, M.D.