ASA Abstracts

ASA Annual Meeting 2014

October 11-15th, 2014
New Orleans, LA

UCLA Reception
October 11th, 2014
6:30 - 8:30PM
W Hotel Downtown New Orleans


Special Session - Best of Abstracts

Session
Date / Time
Abstract # / Title / Authors

SPE 11
Best of Abstracts:
Basic Science
October 13th
8:00AM – 10:00AM
BOS 02: Cardiospinal Reflex Modulation of Ventricular Arrhythmogenesis

Kimberly J. Howard-Quijano, M.D., Kent Yamakawa, M.D., Wei Zhou, Ph.D., Kalyanam Shivkumar, M.D., Ph.D., Aman Mahajan, M.D., Ph.D.

SPE 11
Best of Abstracts:
Basic Science
October 13th
8:00AM – 10:00AM
BOS03: LDL-Receptor Deficient Mice on Western Diet Develop Pulmonary Hypertension and Right Ventricular Dysfunction That Are Prevented by a Novel HDL Mimetic Peptide 4F

Soban Umar, M.D., Ph.D., Kaveh D. Navab, M.D., Rod Partow-navid, B.S., Mohamad Navab, Ph.D., Mansoureh Eghbali, Ph.D.

Oral Presentations

Session
Date / Time
Abstract # / Title / Authors

OR 09-1
Experimental Circulation
October 11th
8:00AM – 9:30AM
A1000 - MiR-98 Regulates Apoptosis in Cardiomyocytes via PGC-1α and STAT3

Jingyuan Li, M.D., Ph.D., Salil Sharma, Ph.D., Mansoureh Eghbali, Ph.D.

OR 09-1
Experimental Circulation
October 11th
8:00AM – 9:30AM
A1005 - Proteomic Analysis Reveals Potential Mechanisms of mitoBKca Channel Translocation to Mitochondria

Jin Zhang, M.S., Zhu Zhang, Ph.D., Enrico Stefani, M.D., Ph.D., Ligia Toro, Ph.D.

OR 17-2
Respiration – Basic Mechanisms, Animal Models and Clinical Science
October 12th
3:00PM – 5:00PM
A2029 - Pulmonary Hypertension Is Associated with Downregulation of miR-193 and Gain of miR-193 Function Decreases Proliferation of Pulmonary Smooth Muscle Cells from PAH Patients

Salil Sharma, Ph.D., Francois Potus, B.Sc., Soban Umar, M.D., Ph.D., Steeve Provencher, M.D., Sébastien Bonnet, Ph.D., Mansoureh Eghbali, Ph.D

OR 17-2
Respiration – Basic Mechanisms, Animal Models and Clinical Science
October 12th
3:00PM – 5:00PM
A2031 - Severe Pulmonary Hypertension in MCT-Rat Model Is Rescued by the Soy Phytoestogen, Genestein via Downregulation of MicroRNA miR-206

Salil Sharma, Ph.D., Alex Centala, Andrea Iorga, B.Sc., Mansoureh Eghbali, Ph.D.

OR 17-2
Respiration – Basic Mechanisms, Animal Models and Clinical Science
October 12th
3:00PM – 5:00PM
A2033 - Oxidized Lipid Treatment Induces Pulmonary Hypertension in Mice via Suppression of MicroRNA miR-19

Salil Sharma, Ph.D., Soban Umar, M.D., Ph.D., Andrea Iorga, B.Sc., Ali Said, Jingyaun Li, Ph.D., Srinivasa Reddy, Ph.D., Mansoureh Eghbali, Ph.D.

OR 10-1
Experimental Neurosciences: Mechanisms
October 13th
3:00PM – 4:30PM
A3044 - The Molecular Transitions that Initiate and Control Excitation-evoked Calcium Influx

Antonios Pantazis, Ph.D., Nicoletta Savalli, Ph.D., Daniel Sigg, M.D., Ph.D., Alan Neely, Ph.D., Riccardo Olcese, Ph.D.

OR 02-2
Anesthetic Action and Biochemistry: Emerging Anesthetics and Analgesics
October 14th
8:00AM – 9:30AM
A4005 - The Rescue Effect of Lipid Emulsion in Bupivacaine-induced Cardiotoxicity Is Blocked by 5-Hydroxydecanoate, a Mitochondrial Selective KATP Antagonist

Parisa Partownavid, M.D., Salil Sharma, Ph.D., Siamak Rahman, M.D., Mansoureh Eghbali, Ph.D.

Poster Discussions

Session
Date / Time
Abstract # / Title / Authors

PD 09-1
Experimental Circulation:
October 12th
1:00PM – 2:30PM
A2066 - Epigenomic Prediction of Cardiovascular Disease Susceptibility: Development of Pre-clinical Diagnostic Markers for Heart Failure

Thomas Vondriska, Ph.D., Emma Monte, B.S., Manuel Rosa-Garrido, Ph.D., Yibin Wang, Ph.D., Haodong Chen, Ph.D.

PD 09-1
Experimental Circulation:
October 12th
1:00PM – 2:30PM
A2067 - Biophysical Properties of mitoBKCa Channel and its Role in Ca2+ Homeostasis

Enrico Stefani, M.D., Ph.D., Enrique Balderas, Ph.D., Ligia Toro, Ph.D.

PD 09-1
Experimental Circulation:
October 12th
1:00PM – 2:30PM
A2068 - 4F Rescues Pulmonary Hypertension by Inducing miR-193 via Suppression of Transcription Factor RXR-alpha

Salil Sharma, Ph.D., Mohamad Navab, Ph.D., Srinivasa Reddy, Ph.D., Mansoureh Eghbali, Ph.D.

PD 04-1
Clinical Circulation: Echo
October 14th
10:00AM – 11:30AM
A4038 - Three Dimensional Strain Imaging Identifies Regional Alterations in Dynamic Left Ventricular Function After Cardiac Surgery

Kimberly J. Howard-Quijano, M.D., Vanessa G. Henke, M.D., Wei Zhou, Ph.D., Kate Lee, B.S., Jennifer Scovotti, M.A., Aman Mahajan, M.D., Ph.D.

Poster Presentations

Session
Date / Time
Abstract # / Title / Authors

PO 06-4
Critical Care
October 11th
8:00AM – 10:00AM
A1110 - Intraoperative Management for Liver Transplantation and Combined Liver-intestinal Transplantation

Victor Xia, M.D., Xiaoxing Song, M.D

PO 09-3
Experimental Circulation
October 11th
10:00AM – 12:00PM
A1178 - The Role of PI3K and STAT3 Signaling Pathways in Intralipid-induced Cardioprotection in Late Pregnancy

Jingyuan Li, M.D., Ph.D., Mansoureh Eghbali, Ph.D.

PO 10-2
Experimental Neurosciences: Mechanisms
October 11th
10:00AM – 12:00PM
A1191 - The α2δ Subunit Couples the Voltage Sensors to the Pore Domain of the Human CaV1.2 Channel Facilitating Its Activation

Nicoletta Savalli, Ph.D., Antonios Pantazis, Ph.D., Daniel Sigg, M.D., Ph.D., Alan Neely, Ph.D., Riccardo Olcese, Ph.D.

PO 10-2
Experimental Neurosciences: Mechanisms
October 11th
10:00AM – 12:00PM
A1192 - The Human BK Channel Encompasses a Cytochrome C-like Structure Within Its Intracellular Gating Ring Domain

Taleh Yusifov, Ph.D., Nicoletta Savalli, Ph.D., Roshni V. Madhvani, Ph.D., Chris S. Gandhi, Ph.D., Riccardo Olcese, Ph.D.

PO 10-2
Experimental Neurosciences: Mechanisms
October 11th
10:00AM – 12:00PM
A1193 - BK Channels can Protect from Oxidative Stress Damage via a Cytochrome C-like Domain

Taleh Yusifov, Ph.D., Nicoletta Savalli, Ph.D., Antonios Pantazis, Ph.D., Riccardo Olcese, Ph.D.

PO 15-3
Pediatric Anesthesia
October 13th
10:00AM – 12:00PM
A3213 - Pre-op Tylenol May Increase Emergence Agitation in Children Undergoing PE Tubes: a Randomized Controlled Trial

Wendy H. Ren, M.D., Michelle L. Keese, M.D., Christine Trieu, M.D., Michelle M. Smith, M.D., Sarah Zacharia, M.S., Alisha West, M.D., Nina Shapiro, M.D., Swati N. Patel, M.D.

PO 09-1
Experimental Circulation
October 13th
1:00PM – 3:00PM
A3280 - A Novel Pre-Clinical Combined Pulmonary Fibrosis and Pulmonary Hypertension Model in Rats

Soban Umar, M.D., Ph.D., Alex Centala, B.S., Andrea Iorga, B.Sc., Salil Sharma, Ph.D., Rajeev Saggar, M.D., Rajan Saggar, M.D., Mansoureh Eghbali, Ph.D.

PO 09-1
Experimental Circulation
October 13th
1:00PM – 3:00PM
A3283 - MaxiK Channel Protein Partners in Human Coronary Artery

Ligia Toro, Ph.D., Min Li, Ph.D., Zhu Zhang, Ph.D., Jure Marijic, M.D., Enrico Stefani, M.D., Ph.D.

PO 09-1
Experimental Circulation
October 13th
1:00PM – 3:00PM
A3284 - Stimulation of Angiogenesis Protects the Hearts in Pregnancy Against Myocardial Ischemia/Reperfusion Injury

Jingyuan Li, M.D., Ph.D., Zoltan Pierre Arany, M.D., Ph.D., Mansoureh Eghbali, Ph.D.

PO 09-1
Experimental Circulation
October 13th
1:00PM – 3:00PM
A3287 - MicroRNA miR-129 Reverses Cardiac Fibrosis in Angiotensin-II-Infused Mice

Salil Sharma, Ph.D., Andrea Iorga, B.Sc., Alex Centala, Jingyaun Li, Ph.D., Mansoureh Eghbali, Ph.D.

PO 09-2
Experimental Circulation
October 14th
8:00AM – 10:00AM
A4115 - More Prone to Develop Hypoxia-Induced Pulmonary Hypertension Than XY Mice Regardless of Their Gonadal Sex

Soban Umar, M.D., Ph.D., Alex Centala, B.S., Andrea Iorga, B.Sc., Salil Sharma, Ph.D., Jingyuan Li, Ph.D., Arthur P. Arnold, Ph.D., Mansoureh Eghbali, Ph.D.

PO 09-2
Experimental Circulation
October 14th
8:00AM – 10:00AM
A4117 – Role of BK Channel β Subunits in Mitochondrial Function and Protection of the Heart from Ischemia-reperfusion Injury

Christopher O. Ortiz, M.D., Ph.D., Enrique Balderas, Ph.D., Enrico Stefani, M.D., Ph.D., Ligia Toro, Ph.D.

PO 14-4
Patient Safety and Practice Management
October 14th
8:00AM – 10:00AM
A4137 - Situational Awareness Errors in Anesthesia Malpractice Claims

Amanda R. Burden, M.D., Karen B. Domino, M.D., M.P.H., Shawn L. Mincer, MSW, Karen L. Posner, Ph.D., Randolph H. Steadman, M.D., M.S., Klaus J. Wagner, M.D., Christian M. Schulz, M.D

Medically Challenging Case Presentations

Session
Date / Time
Title / Authors

MCC 04
October 11th
3:00PM – 4:30PM
12-Year-Old Male with Acute Bilateral Vocal Cord Paralysis with Worsening Stridor after Tetralogy of Fallot Repair

Jack C. Buckley, M.D.

MCC 06
October 12th
10:30AM – 12:00PM
A Case of Fibrolamellar Hepatocellular Carcinoma Invading into the Right Heart

Jessica R. Hiruma, M.D., Zarah Antongiorgi, M.D., Komal D. Patel, M.D.

MCC 08
October 12th
3:00PM – 4:30PM
Acute Dystonic Reaction to General Anesthesia with Propofol: A Case Report

Rachel C. Steckelberg, M.D.,M.P.H., David Tsiang, M.D., Nir Hoftman, M.D.

MCC 10
October 13th
10:30AM – 12:00PM
Line-associated DVT Removal with Novel AngioVac Aspiration Device via Fontan and Glenn Shunts

Chonghua Wang, M.D., Steven Tham, M.D., John Moriarty, M.D., Komal Patel, M.D.

MCC 11
October 13th
1:00PM – 2:30PM
Successful Resuscitation with Extracorporeal Membrane Oxygenation Following Massive Acute Pulmonary Embolism During Vacuum-assisted Thrombectomy

Rachel C. Steckelberg, M.D., Jun Sasaki, M.D.

Hands-on Workshops

Session
Date / Time
Title / Faculty

Clinical 804
October 11th
8:00AM – 11:00AM
Acupuncture Workshop

Eric Hsu, M.D.

Clinical 809
October 11th
1:00PM – 4:00PM
Pacemakers and ICDs

Aman Mahajan, M.D., Ph.D., Jonathan Ho, M.D., Kimberly Howard-Quijano, M.D., Jason Chua, M.D., Prince Neelankavil, M.D.

Clinical 825
October 13th
8:00AM – 11:00AM
Critical Care Ultrasonography for the Perioperative Physician

Joseph Meltzer, M.D.

90 Minute Panels

Session
Date / Time
Title / Lead Speaker

PN-42
October 11th
1:00PM – 2:30PM
Red Blood Cells: Good, Bad, and Ugly and Some Solutions

Jonathan Jahr, M.D. – Solutions (including Blood Substitutes)

PN-45
October 11th
3:30PM – 5:00PM
Optimizing Perioperative Hepatic Function

Randolph Steadman, M.D., M.S. – Perioperative Optimization and Rescue

PN-93
October 14th
3:30PM – 5:00PM
Sugammadex: Are We Finally There? Update on Unmet Medical Need, Clinical Use in Europe and Regulatory Progress

Jonathan Jahr, M.D. – Science and Regulatory Stalemate and Solution

Refresher Course

Session
Date / Time
Title / Faculty

Lecture 431
October 14th
3:30PM – 4:30PM
Trauma Anesthesia and Operative Resuscitation

Moderator: Joshua Tobin, M.D.

Point-Counterpoint

Session
Date / Time
Title / Faculty

PC-18
October 14th
1:30PM – 2:30PM
Hypotensive Resuscitation

Moderator: Joshua Tobin, M.D.

PC-20
October 14th
3:00PM – 4:30PM
Electronic Health Records Improve Patient Safety – or Do They?

Speaker - Pro: James Moore, M.D. – Electronic Health Records Improve Patient Safety and Quality of Care