Olcese Lab

Ion channels and cellular excitability are central themes of the research programs developed in the Olcese laboratory, which integrates molecular-level biophysical studies with organ-wide phenomena of clinical significance, such as cardiac arrhythmias. The quantitative tools of biophysics are used in a translational context in combination with protein biochemistry, molecular biology, fluorescence spectroscopy, and electrophysiology, to understand the role of ion channels and their mechanisms of electrical and chemical sensing in health and disease.